I might have had this problem for a while... since I don't mess with video settings all the time. But I tried to add my old monitor (3 monitor setup) and I realized I couldn't open Catalyst Control Center.
I'm running Win 7 64-bit with a 7950.
Per troubleshooting websites, this is what i've done so far:
remove old/add newest drivers
remove drivers, go into safe mode and delete any ATI assembly codes (i had zero), reinstall
clean out .net frameworks via cleanup tool, reinstalled .net 4.0 and older 12.10 drivers
clean out .net frameworks via cleanup tool, reinstalled .net 4.5 with newest drivers.
Still can't open CCC.
I'm reading that there can be issues with .net and ati drivers, but I haven't hit the sweet spot yet.
Help? Advice? Am I missing something?